PRAME (PReferentially expressed Antigen in MElanoma), also known as Preferentially expressed antigen in Melanoma, is a tumor-associated antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. Normal tissues show low or no expression except in testis, ovary, placenta, adrenals and endometrium. Therefore, it is a member of the family of cancer testis antigens. PRAME is also expressed in malignant cells, including leukaemias, Hodgkin’s lymphoma and breast cancer. This antibody may be used as melanoma marker to differentiate benign from malign tumors.
Catalog No. | Contents | Volume |
ILM0005-C01 | PRAME | 0,1 ml concentrate |
ILM0005-C05 | PRAME | 0,5 ml concentrate |
ILM0005-C1 | PRAME | 1,0 ml concentrate |